The Two and a Half Men actor was reportedly high on drugs and spent $10 000 alone on a prostitute called Ginger during his 48-hour stay at the Hugh Hefner Sky Villa inside the Fantasy Tower at the Palms Casino Resort.
A source told RadarOnline.com: "Ginger said Charlie was high on cocaine when she got to the room and continued to do drugs in front of her. He was totally out of it and clearly had been partying all night long.
"Charlie told Ginger this wasn't just a one night stand and that he plans to reconnect with her the next time he is in Las Vegas. From what she has said, he had a very good time with her and she is just his type."
Along with Ginger, 45-year-old Charlie is also said to have spent $8 000 each on two other escorts.
The actor reportedly enjoyed a "revolving door" of gorgeous women visiting him in the suite on the same weekend, among them porn star Bree Olsen and Jesse James's ex-mistress Michelle 'Bombshell' McGee.
Charlie's latest blow-out came after he fired his sober coach, who had been hired after he trashed a New York hotel room and was found naked by police.
A source said: "The sober coach never went back to work for Charlie. He has not heard from Charlie since he told him not to start New Year's Day."
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South AfricaDiscovery Partner Markets
TownhousesR 1 750 000
TownhousesR 3 695 000
HousesR 2 200 000