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Jane Carrey - the actor's 23-year-old daughter with first wife Melissa Womer - and Alex Santana have ended their year-long marriage but have vowed to stay friends for the sake of their nine-month-old son Jackson Riley.
A spokesperson for Jim told In Touch Weekly magazine: "The couple will remain friends, as well as devoted parents to their nine-month-old son, Jackson Riley."
No reason for the split has been given.
Jane is said to have taken Jackson to visit her 48-year-old father in New York, where he is currently filming Mr Popper's Penguins.
Jim - who split from long-term girlfriend Jenny McCarthy earlier this year - recently spoke of his joy at being a grandfather and admitted the baby had given him a new focus on life.
He said: "I love being granddaddy, granddaddy Jim. It's very odd, it's not something I expected at this age to be.
"I just get a lot of joy, a lot of joy from that little boy , he's just magical. It's the greatest feeling in the world and as you get older, your connection to these things gets so intense . You just go, 'Without this, I die.'"
