1. Mulholland Dr. (2001)
The first intimate encounter between Naomi Watts and Laura Elena Harring is soft and sweet ... but because this is a David Lynch movie, naturally the relationship between these two women becomes darker and more complicated. Watts, as aspiring starlet Betty Elms (at this point in the film, at least), gets tangled up with Harring's gorgeous amnesiac Rita. As the two embark on an adventure, playing girl-detective to solve the mystery of Rita's past, their fear and loneliness lead to a kiss which leads to one of the loveliest lesbian scenes ever filmed. In a movie full of twists, this is a rare moment of pure, instinctive emotion.