The Weinstein Co. tells The Associated Press that Obama will screen the film Thursday at the White House. Mandela's daughters Zindzi and Zenani Mandela will join, as will the film's stars, Idris Elba and Naomie Harris.
The film will also screen 20 November at the Kennedy Center, with Clinton hosting the gala.
Though there have been other films about the former South African president, Mandela: Long Walk to Freedom has long had Mandela's approval and the cooperation of his family.
It premiered Sunday in Johannesburg with much of Mandela's family in attendance.
Mandela opens in theaters on 29 November.