First look at the cast of Murder on the Orient Express

Cape Town - Agatha Christie's bestselling novel, Murder on The Orient Express gets another big screen remake. 

They story centres on the investigation of a fatal stabbing on board a train from Istanbul to Paris. 

And now we have a first look at the cast who appear on the cover of Entertainment Weekly. 

All aboard! ???? We have your exclusive first look at @orientexpressmovie! ?? Starring #PenelopeCruz, #JohnnyDepp, #DaisyRidley, #JoshGad and more, it is definitely the most star-studded thriller of the year. Click the link in our bio to get all the details and don't forget to pick up an issue on newsstands starting Friday, May 5. #OrientExpressMovie ??: Frank Ockenfels 3/Fox

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Kenneth Branagh takes the lead as Hercule Poirot.

Other A-list cast members include Johnny Depp, Michelle Pfeiffer, Daisy Ridley, Penelope Cruz, Judi Dench, Josh Gad and William Dafoe.

See the pictures here:

#AgathaChristie's most glamorous—and most gruesome—mystery is coming to life! ??????Swipe through for your first look at star-studded thriller #MurderOnTheOrientExpress! Click the link in our bio for more stunning photos. ??: Nicola Dove/Fox

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The film, directed by Branagh, is expected to hit cinemas in November this year. 

A screen adaption of the film was first done in 1974. It starred Alber Finney, Lauren Bacall, Ingrid Bergman and Sean Connery.