The crowd cheered when host, US comedian Marlon Wayans, arrived on stage in a bead-studded ricksha... and giggled when he battled to pronounce “KwaZulu-Natal” in his opening speech.
Afropop group Mafikizolo continued with their winning streak when they were crowned best group.
Other local artists who clinched top honours included Uhuru featuring DJ Buckz, Professor, Oskido, Uri-Da-Cunha, for best collaboration, and Goldfish for best pop artist.
Crowd favourite Tiwa Savage from Nigeria won best female artist to wild applause. In her speech, she thanked her "handsome husband".
Another local win for best alternative act went to Gangs of Ballet. DJ Fresh put in an appearance to hand out the award best hip-hop artist award, which went to Sarkodie from Ghana.
US rappers Trey Songz and Miguel also performed at the awards.
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