The 62-year-old Bee Gee's star's condition is said to be so serious that brother Barry, 65, has flown in from Tennessee, America, to make an emergency visit.
A source told The Sun newspaper: "They fear it may be the last time they'll see Robin. His recovery and determination has been remarkable, but there's been a turn for the worse.
"His body's taken a hell of a beating. The doctors fear for him but he's determined to battle on."
The teetotal vegan was first diagnosed with cancer in April 2011 after being admitted to hospital with abdominal pains, but just last month his son Robin-John - know as RJ - revealed the chemotherapy had wiped out all signs of the disease.
Talking about the moment he heard the news, RJ said: "I leant over the hospital bed and I kissed him on the forehead, looked him in the eyes and just said, 'I love you'.
"Then we sat together for ages, just taking it all in and being together without saying anything. It was the best news we could have hoped for.
"It was the most beautiful feeling and instantly life was so, so much better."
24.com publishes all comments posted on articles provided that they adhere to our Comments Policy. Should you wish to report a comment for editorial review, please do so by clicking the 'Report Comment' button to the right of each comment.
The family of Marvin Gaye has won a round in a court battle over allegations that last year's hit song Blurred Lines ripped off the late Motown legend's work. Read More »
Michael Jackson's Thriller has been revealed as the scariest song of all time. Read More »
New music video!
Did you know?
A scary night!
Guns N' Roses guitarist!
Cape TownAnchor Executive Recruitment (Pty) Ltd
Cape TownWest Coast Personnel
HousesR 2 500 000
TownhousesR 6 900 000
HousesR 18 000 000