Artists including British pop band Florence and the Machine, US pop singer Colbie Caillat, pianist Herbie Hancock and singer-songwriter Elvis Costello will also perform at the December 11 show.
Washington said on Thursday he was "honoured to attend" the Nobel Peace Prize Concert "to help spread the message of global peace".
Last year, actor Will Smith and his actress wife Jada Pinkett Smith co-hosted the concert, honouring the 2009 laureate and Smith fan Barack Obama.
The winner of the 2010 Nobel Peace Prize will be announced in Oslo on October 8. The award is presented on December 10.
Britain's Prince Harry will visit South Africa and Lesotho from 26 November to 4 December. Read More »
Charlize Theron has adopted her second child, an African-American newborn named August, reports say. Read More »
A coffee snob.
A new beer.
Welcome in SA.
George - KnysnaSanlam
SandtonDante Personnel RecruitmentR12 000 - R18 000 Per Month
HousesR 4 550 000
HousesR 2 850 000
HousesR 7 500 000